Imaging defect formation in the template growth of NiSi2/Si(111): An application of quantum size microscopy.
Published in Physical Review B
Partial nucleotide sequences and expression patterns of frog (Rana pipiens) ephrin-A2 and ephrin-A5 mRNA.
Published in Developmental Brain Research
We have generated 362 bp and 547 bp partial sequences for Rana pipiens ephrin-A2 and ephrin-A5 mRNA, respectively. Translation homologies for the comparable segments of cDNA of chicken, mouse and human are 90.8, 86.9 and 84.4% for the ephrin-A2 sequence and 85.7, 85.0 and 85.0% for the ephrin-A5 sequence. Digoxigenin-labeled riboprobes were prepare...
RNAi reveals doublecortin is required for radial migration in rat neocortex.
Published in Nature Neuroscience
Mutations in the doublecortin gene (DCX) in humans cause malformation of the cerebral neocortex. Paradoxically, genetic deletion of Dcx in mice does not cause neocortical malformation. We used electroporation of plasmids encoding short hairpin RNA to create interference (RNAi) of DCX protein in utero, and we show that DCX is required for radial mig...
Enhanced plasticity of retinothalamic projections in an ephrin-A2/A5 double mutant.
Published in Journal of Neuroscience
Ascending sensory information reaches primary sensory cortical areas via thalamic relay neurons that are organized into modality-specific compartments or nuclei. Although the sensory relay nuclei of the thalamus show consistent modality-specific segregation of afferents, we now show in a wild-type mouse strain that the visual pathway can be surgica...
Genome 10K: a proposal to obtain whole-genome sequence for 10,000 vertebrate species.
Published in Journal of Heredity
The human genome project has been recently complemented by whole-genome assessment sequence of 32 mammals and 24 nonmammalian vertebrate species suitable for comparative genomic analyses. Here we anticipate a precipitous drop in costs and increase in sequencing efficiency, with concomitant development of improved annotation technology and, therefor...
The potential of endogenous neuronal replacement in developing cerebral cortex following hypoxic injury.
Published in Experimental Neurology
Probing the role of PrP repeats in conformational conversion and amyloid assembly of chimeric yeast prions.
Published in Journal of Biological Chemistry
Oligopeptide repeats appear in many proteins that undergo conformational conversions to form amyloid, including the mammalian prion protein PrP and the yeast prion protein Sup35. Whereas the repeats in PrP have been studied more exhaustively, interpretation of these studies is confounded by the fact that many details of the PrP prion conformational...
