HAL: a hierarchical format for storing and analyzing multiple genome alignments.
Published in Bioinformatics
Gene structure-based splice variant deconvolution using a microarray platform.
...Published in Bioinformatics
Comparative assembly hubs: web-accessible browsers for comparative genomics.
...Published in Bioinformatics
Motivation: Researchers now have access to large volumes of genome sequences for comparative analysis, some generated by the plethora of public sequencing projects and, increasingly, from individual efforts. It is not possible, or necessarily desirable, that the public genome browsers attempt to curate all these data. Instead, a wealth of powerful ...
Classifying G-protein coupled receptors with support vector machines.
Published in Bioinformatics
Motivation: The enormous amount of protein sequence data uncovered by genome research has increased the demand for computer software that can automate the recognition of new proteins. We discuss the relative merits of various automated methods for recognizing G-Protein Coupled Receptors (GPCRs), a superfamily of cell membrane proteins. GPCRs are fo...
